Carpal tunnel syndrome - Treatments

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You should begin treatment for your carpal tunnel syndrome as early as possible. Wearing a special splint on the affected wrist might improve your symptoms. But if damage to the nerve in your hand is already severe, you may need an operation straight away.

  • If your carpal tunnel syndrome is mild or moderate, your symptoms might improve after wearing a splint that keeps your wrist from bending.
  • If you have severe carpal tunnel syndrome, you may need an operation straight away to prevent more permanent nerve damage.
  • About 9 in 10 people who have surgery to release their carpal tunnel are better a year later. But we don't know how long the benefits last.
  • A steroid injection into your wrist may reduce your pain and swelling.

We've looked closely at the research and ranked the treatments into categories, according to whether they work. For help in deciding what treatment is best for you, see .

Treatments that are likely to work

Steroids

If your symptoms are severe, a steroid injection into your carpal tunnel will probably make your hand, arm and wrist feel less painful and swollen.[1] The full name for these medicines is corticosteroids.

Steroid injections may work better than surgery in the short term. But the effects of steroid injections may not last as long as the effects of surgery.

Most of the studies into this treatment lasted only for three months or less.[1] In one study that lasted for a year, 94 percent of people said they had a big improvement in symptoms after the injection, but that had dropped to 70 percent after a year. About 75 percent of people who had surgery said they had a big improvement in symptoms after the operation, and that stayed the same for the whole year.[2]

Another study looked at having a second injection two weeks after the first. It found that two injections didn't work better than one.[3]

There is a small risk that your tendon might rupture or the nerve could be hit by mistake when steroids are injected into your carpal tunnel.[4] [5]

The steroid injection is often combined with a local anaesthetic, so the injection should be painless.

Some research has shown that taking steroid tablets may ease the pain and swelling in your hand, arm and wrist after a couple of weeks.[6] [7] [8] Doctors don't often use tablets to treat carpal tunnel syndrome because injections probably work better.[9] Also, there may be serious side effects if you take steroid tablets for a long time.[10]

Treatments that need further study

Wrist splints

Your doctor may suggest that you wear a splint to keep your wrist from bending. This is often suggested as a first treatment. One study (a randomised controlled trial) found that wearing a splint at night improved symptoms after two weeks.[11] And the benefits continued for four weeks. But splints do not work as well as surgery.[12]

We don't know if wrist splints work better if they are worn all the time, during the day or just at night. You might find it easiest to wear your splints at night and only during the day when you're relaxing in front of the television.

You can buy wrist splints that support your wrist at a natural, slight angle. Or you can ask your doctor to have a splint custom-made to keep your wrist in a straight, neutral position. But there's not enough research to say what type of splint works best. One small study found no difference in symptoms between the two types of splints.[13] Another small study found that custom-made splints worked better.[14]

Some people feel pins and needles in their hand for a short while when they take off their splint.[11]

Nonsteroidal anti-inflammatory drugs

Nonsteroidal anti-inflammatory drugs (NSAIDs) are painkillers that also reduce inflammation. They include drugs like ibuprofen (which you can buy over the counter) and naproxen and diclofenac (which you can get only with a prescription). But there hasn't been enough research to say if an NSAID will make your hand hurt less. One summary of the research found these drugs probably won't work any better than a dummy treatment (a placebo) to treat your carpal tunnel syndrome.[6]

But you may find that taking an NSAID helps if you also have a lot of pain and swelling in your fingers caused by tendon problems (doctors call this tendonitis).

NSAIDs have side effects, including nausea and diarrhoea. Taking high doses of some NSAIDs every day for a long time can increase your risk of a heart attack or a stroke. This isn't likely to be a problem if you take NSAIDs for a short time to treat pain. But if you'd like to read more, see Warnings about side effects of NSAIDs.

Vitamin B-6 (pyridoxine)

Some people try taking a daily dose of vitamin B-6 (pyridoxine) to relieve their numbness, tingling and pain from carpal tunnel syndrome. You can buy this vitamin supplement from chemists or health food shops. But there hasn't been enough research to tell us if vitamin B-6 can really help.

Two small studies (randomised controlled trials) showed that taking vitamin B-6 for up to 12 weeks didn't work any better than taking a dummy treatment (placebo).[15] [16] But these studies weren't very good quality, so the results may not be reliable. The studies didn't mention if the people who took vitamin B-6 to treat their carpal tunnel syndrome had any side effects. We know that numbness, tingling and not being able to walk properly were common side effects in people who took part in studies of vitamin B-6 at higher doses (200 milligrams).[17] Doses up to 10 milligrams a day are considered safe.[11]

Exercises

There are exercises you can try that are meant to relieve the trapped nerve in your wrist. You stretch your fingers and wrist in different positions to see if doing this can release the pressure on your nerve. The exercises are known as nerve and tendon gliding exercises. But there hasn't been enough research to say if doing these exercises helps with carpal tunnel syndrome.

One small study (a randomised controlled trial) looked at people who did these exercises five times a day for four weeks.[17] They also wore a wrist splint during the day and night. The people who exercised their fingers and wrist had a stronger grip after eight weeks. But their other symptoms were just as severe as those of people who hadn't done any exercises.

We don't know if nerve and tendon gliding exercises could harm you, because the research doesn't tell us. But there may be a risk that some exercises could make your condition worse. It's important to discuss what exercises you should be doing with a physiotherapist or another health professional.[18]

Ultrasound

Physical therapists sometimes use ultrasound (heat from sound waves) to treat carpal tunnel syndrome. There hasn't been enough good research to say whether ultrasound can heal your wrist.[19]

One study (a randomised controlled trial) found that people who had ultrasound were more likely to get better or recover completely after six months.[20] But this study wasn't high quality. Another small study found that having ultrasound five times a week for two weeks didn't make any difference to people's symptoms.[21]

Acupuncture

Some people try acupuncture for carpal tunnel syndrome. But there hasn't been any good research to say whether it works or not.

Acupuncture is based on the belief that energy called qi (sounds like 'chee') travels around the body along special pathways called meridians. When this energy flow gets blocked, you feel pain and have health problems. Acupuncture uses sterile needles to unblock this energy.

Massage

Some people try massage therapy for carpal tunnel syndrome. But there hasn't been any good research to say whether or not it works.

Massage involves rubbing and stroking the skin and flesh over the affected area, to try to ease muscle tension.

Treatments that work, but whose harms may outweigh benefits

Surgery

There's a good chance that having surgery to release the pressure on the nerve inside your carpal tunnel will cure your carpal tunnel syndrome. In studies, about 8 in 10 people said they were better three months after the operation. This compares with about 5 in 10 people who had wrist splints instead of an operation. After a year, about 9 in 10 people who had surgery said they were better. The improvement lasted for at least 18 months.[12]

Studies comparing steroid injections with an operation found people were more likely to have a big improvement three months later with injections. But after six months, the effects of the injections had worn off for some people. Surgery was as good as injections after six months.[2]

But all operations have some risks. You'll need to think about whether you want to have the operation straight away or whether you want to try other treatments first. Your doctor can help you make this decision.

Surgery involves cutting free your carpal ligament (band of tissue) from your median nerve. The operation is usually done under local anaesthetic (which numbs your arm and hand but doesn't send you to sleep). You should be able to go home the same day.

You can have open or keyhole surgery for this operation. In open surgery, the surgeon makes a cut in your wrist up to 5 centimetres (2 inches) long. With keyhole surgery, the surgeon makes a small hole in your wrist and puts in a tube called an endoscope. The surgeon uses a tiny camera and instruments on the end of the tube. We don't know if one of these operations works better than the other. A large summary of the research (called a systematic review) found no difference in symptoms after either operation.[22] But some studies show people who have keyhole surgery can go back to work and get back to normal sooner.[22] [23]

Sometimes doctors advise wearing a wrist splint after surgery. But research shows this probably won't speed up your recovery.[24] The splint may cause more temporary pain and make your scar tender. You should be able to return to work sooner if you don't wear a splint after your operation.

Many people complain of side effects after surgery, but most are mild and don't last long.[25]

  • Keyhole surgery may cause more temporary nerve problems, such as numbness and tingling, but you might get more problems from your wound if you have open surgery.
  • It's possible the pain from your scar or stiffness at the wrist may end up worse than your carpal tunnel syndrome. Your wrist may also lose strength because your carpal ligament is cut. But these serious side effects are rare.

There's not enough research to tell us whether you might get other problems from the surgery later on. We also don't know if your carpal tunnel syndrome might come back several years after surgery. If you need another operation, this might not be so successful and the risk of having problems because of it is greater.[18]

Treatments that are unlikely to work

Additional surgery

Some of the tissue around your nerve can also be cut when you have surgery for carpal tunnel syndrome. This is to try to free up the nerve more than by just cutting the carpal ligament. Doctors call this procedure internal neurolysis. This procedure isn't done very often nowadays.

The research shows this extra surgery is unlikely to help. After a year, people who had this additional surgery had symptoms similar to those of people who had just the basic operation.[26] [27] The complications from both kinds of operations were similar.[28]

Diuretics

Some people get fluid retention (their body holds onto extra fluid) when they are pregnant or starting the menopause. This might cause or worsen carpal tunnel syndrome. Swelling around your carpal tunnel may put pressure on the nerve to your hand. So doctors sometimes advise trying a diuretic drug (water pill) to stop your body holding onto extra fluid.

But taking a diuretic drug probably won't improve your carpal tunnel syndrome. Two studies (randomised controlled trials) show people who took a diuretic for four weeks felt no better than those who took a dummy treatment (a placebo) or an anti-inflammatory painkiller.[29] [30]

Some people in the studies said they felt sick or had stomach pain when taking a diuretic, but the side effects weren't serious.

References

  1. Marshall S, Tardif G, Ashworth N. Local corticosteroid injection for carpal tunnel syndrome (Cochrane review). In: Cochrane Library: Issue 4, 2006. Wiley, Chichester, UK.
  2. Ly-Pen D, Andreu JL, et al Surgical decompression versus local steroid injection in carpal tunnel syndrome: a one-year, prospective, randomized, open, controlled clinical trial. Arthritis and Rheumatism. 2005; 52: 612–619.
  3. Wong SM, Hui AC, Lo SK, et al. Single vs. two steroid injections for carpal tunnel syndrome: a randomised clinical trial. International Journal of Clinical Practice. 2005; 59: 1417-1421
  4. Babu SR, Britton JM. The role of steroid injection in the management of carpal tunnel syndrome. Journal of Orthopaedic Rheumatology. 1994; 7: 59-60.
  5. Katz JN, Simmons BP. Clinical practice. Carpal tunnel syndrome. New England Journal of Medicine. 2002; 346: 1807-1812.
  6. Gerritsen AAM, de Krom MCTFM, Struijs MA, et al. Conservative treatment options for carpal tunnel syndrome: a systematic review of randomised controlled trials. Journal of Neurology. 2002; 249: 272-280.
  7. Hiu ACF, Wong SM, Wong KS, et al. Oral steroid in the treatment of carpal tunnel syndrome. Annals of the Rheumatic Diseases. 2001; 60: 813-814.
  8. Mishra S, Prabhakar S, Lal V, et al. Efficacy of splinting and oral steroids in the treatment of carpal tunnel syndrome: a prospective randomized clinical and electrophysiological study. Neurology India. 2006; 54: 286–290.
  9. Marshall S, Tardif G, Ashworth N. Local corticosteroid injection for carpal tunnel syndrome (Cochrane review). In: Cochrane Library. Update Software, Oxford, UK.
  10. British National Formulary. Corticosteroids. March 2007. BNF 53. British Medical Association and Royal Pharmaceutical Society of Great Britain. Available at http://www.bnf.org/ (accessed on 12 June 2008).
  11. Manente G, Torrieri F, Di Blasio F, et al. An innovative hand brace for carpal tunnel syndrome: a randomised controlled trial. Muscle Nerve. 2001; 24: 1020-1025.
  12. Gerritsen AA, et al Splinting versus surgery in the treatment of carpal tunnel syndrome. Journal of the American Medical Association. 2002; 288: 1245–1251.
  13. Burke TD, Burke MM, Stewart GW, et al. Splinting for carpal tunnel syndrome: in search of the optimal angle. Archives of Physical and Medical Rehabilitation. 1994; 75: 1241-1244.
  14. Brininger TL, Rogers JC, Holm MB, et al. Efficacy of a fabricated customized splint and tendon and nerve gliding exercises for the treatment of carpal tunnel syndrome: a randomized controlled trial. Archives of Physical Medicine and Rehabilitation. 2007; 88: 1429-1435.
  15. Spooner GR, Desai HB, Angel JF, et al. Using pyridoxine to treat carpal tunnel syndrome: randomized control trial. Canadian Family Physician. 1993; 39: 2122-2127.
  16. Stransky M, Rubin A, Lava NS, et al Treatment of carpal tunnel syndrome with vitamin B6: a double-blind study. Southern Medical Journal. 1989; 82: 841–842.
  17. Akalin E, El O, Peker O, et al. Treatment of carpal tunnel syndrome with nerve and tendon glidingexercises. American Journal of Physical and Medical Rehabilitation. 2002;81:108-113.
  18. Fatami T, Kobayashi A, Utika T, et al. Carpal tunnel syndrome; its natural history. Hand Surgery. 1997; 2: 129-130.
  19. Gerritsen AAM, de Krom MCTFM, Struijs MA, et al. Conservative treatment options for carpal tunnel syndrome: a systematic review of randomised controlled trials. Journal of Neurology. 2002; 249: 272-280.
  20. Ebenbichler GR, Resch KL, Nicolakis P, et al Ultrasound treatment for treating the carpal tunnel syndrome: randomised “sham” controlled trial. BMJ. 1998; 316: 731–735.
  21. Oztas O, Turan B, Bora I, et al Ultrasound therapy effect in carpal tunnel syndrome. Archives of Physical Medicine and Rehabilitation. 1998; 79: 1540–1544.
  22. Scholten RJ, Mink van der Molen A, Uitdehaag BM, et al. Surgical treatment options for carpal tunnel syndrome. In: The Cochrane Library: Wiley, Chichester, UK.
  23. Cook AC, Szabo RM, Birkholz SW, et al. Early mobilization following carpal tunnel release: a prospective randomized study. Journal of Hand Surgery (British volume). 1995; 20: 228-230.
  24. Mackinnon SE, McCabe S, Murray JF, et al. Internal neurolysis fails to improve the results of primarycarpal tunnel decompression. Journal of Hand Surgery (American volume). 1991; 16: 211-218.
  25. Gerritsen AA, Uitdehaag BMJ, van Geldere D, et al. Systematic review of randomised clinical trials of surgical treatment for carpal tunnel syndrome. British Journal of Surgery. 2001; 88: 1285-1295.
  26. Lowry WE Jr, Follender AB. Interfascicular neurolysis in the severe carpal tunnel syndrome: a prospective,randomized, double-blind, controlled study. Clinical Orthopaedics and Related Research. 1988; 227: 251-254.
  27. Chapell R, Coates V, Turkelson C Poor outcome for neural surgery (epineurotomy or neurolysis) for carpal tunnel syndrome compared with carpal tunnel release alone: a meta-analysis of global outcomes.
  28. Lowry WE Jr, Follender AB Interfascicular neurolysis in the severe carpal tunnel syndrome. A prospective, randomized, double-blind, controlled study. Clinical Orthopaedics and Related Research. 1988; 227: 251-254.
  29. Chang MH, Chiang HT, Lee SS, et al. Oral drug of choice in carpal tunnel syndrome. Neurology. 1998; 51: 390-393.
  30. Pal B, Mangion P, Hossain MA, et al. Should diuretics be prescribed for idiopathic carpal tunnel syndrome? Results of a controlled trial. Clinical Rehabilitation. 1988; 2: 299-301.

Glossary

menopause
When a woman stops having periods, it is called the menopause. This usually happens around the age of 50.
local anaesthetic
A local anaesthetic is a painkiller that's used to numb one part of your body. You usually get local anaesthetics as injections.
randomised controlled trials
Randomised controlled trials are medical studies designed to test whether a treatment works. Patients are split into groups. One group is given the treatment being tested (for example, an antidepressant drug) while another group (called the comparison or control group) is given an alternative treatment. This could be a different type of drug or a dummy treatment (a placebo). Researchers then compare the effects of the different treatments.
NSAIDs
NSAID stands for nonsteroidal anti-inflammatory drug. NSAIDs help with pain, inflammation and fever. They are called 'nonsteroidal' because they don't contain any steroids. Aspirin and ibuprofen are both NSAIDs.
inflammation
Inflammation is when your skin or some other part of your body becomes red, swollen, hot and sore. Inflammation happens because your body is trying to protect you from germs, from something that's in your body and could harm you (like a splinter) or from things that cause allergies (these things are called allergens). Inflammation is one of the ways in which your body heals an infection or an injury.
placebo
A placebo is a 'pretend' or dummy treatment that contains no active substances. A placebo is often given to half the people taking part in medical research trials, for comparison with the 'real' treatment. It is made to look and taste identical to the drug treatment being tested, so that people in the studies do not know if they are getting the placebo or the 'real' treatment. Researchers often talk about the 'placebo effect'. This is where patients feel better after having a placebo treatment because they expect to feel better. Tests may indicate that they actually are better. In the same way, people can also get side effects after having a placebo treatment. Drug treatments can also have a 'placebo effect'. This is why, to get a true picture of how well a drug works, it is important to compare it against a placebo treatment.
heart attack
Doctors call a heart attack an acute myocardial infarction (or acute MI). This is the name for the damage that occurs to the heart muscle if it isn't getting enough blood and oxygen because a branch of the coronary arteries is blocked. During a heart attack, you may have pain or heaviness over your chest, and pain, numbness or tingling in your jaw and left arm.
stroke
You have a stroke when the blood supply to a part of your brain is cut off. This damages your brain and can cause symptoms like weakness or numbness on one side of your body. You may also find it hard to speak if you've had a stroke.
physiotherapist
A physiotherapist is a health professional who is trained to use physical activity and exercises to help people's bodies heal.
ultrasound
Ultrasound is a tool doctors use to create images of the inside of your body. An ultrasound machine sends out high-frequency sound waves, which are directed at an area of your body. The waves reflect off parts of your body to create a picture. Ultrasound is often used to see a developing baby inside a woman's womb.
systematic reviews
A systematic review is a thorough look through published research on a particular topic. Only studies that have been carried out to a high standard are included. A systematic review may or may not include a meta-analysis, which is when the results from individual studies are put together.

© BMJ Publishing Group Limited ("BMJ Group") 2007. All rights reserved

This information does not replace medical advice. If you are concerned you might have a medical problem please ask your Boots pharmacy team in your local Boots store, or see your doctor.

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