Autism - What is it?

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You may have noticed that your child was different, even as a small baby. Perhaps he or she seems less involved with the world around them than other children. And maybe your child doesn't show much interest in people.

You may be trying to work out if the differences you have noticed are autism. Or you may have been told that your child has autism and want to find out the best way to help them.

Key points about autism

  • If your child has autism, they may not learn to speak at the usual age. And they may have problems communicating in other ways too.
  • Also, your child may not be interested in other people. And he or she may have set ways of behaving and may do the same activity over and over again.
  • Usually, these signs show up before your child is 3 years old.
  • We don't know what causes autism. But it's linked to how your child's brain works. It's not caused by anything you as a parent might have done.
  • About 6 in 1,000 children have an autistic spectrum disorder. That means they have autism or a related condition. Some children have only mild symptoms and some have bad symptoms.
  • There isn't any cure for autism. Your child will always have it. But getting treatment early on can help make a difference to your child's life.[1]
  • There hasn't been much good research on which treatment works best.

How children develop

Children with autism usually grow and look like other children but they don't develop the skills to get on with other children.Children change in many ways as they get older. They grow physically. For example, they put on weight and get taller and stronger.

But they grow in other important ways too. They learn how to speak, smile and get on with people in other ways, such as playing. Doctors call all of these changes development.

These changes normally happen by specific ages. So you may hear them called developmental milestones. A milestone is just a way to tell how far you have come.

Doctors watch for milestones to tell if your child is developing properly. You can watch for them too. If you are worried about autism, here are some to watch for.[2] [3] [4] [5]

  • By the age of 2 months, most babies smile.
  • By 9 months, most follow your finger if you point to something.
  • By 1 year, most babble and point to things they want.
  • By 2 years, most can speak phrases of two words on their own (not copying you) and can play pretend.

But children don't always follow this pattern exactly. Also, they can be slow to reach certain milestones but not others. Ask your doctor if you think your child is falling behind in any way.

Skills like speaking, smiling and getting on are controlled by your child's brain. It gets bigger and forms new pathways as your child gets older.

What happens in autism?

With autism, your child's brain doesn't work as it should.[1] This affects how your child develops in many ways. So doctors call autism a pervasive developmental disorder (PDD for short).

On the outside, children with autism usually grow and look like other children. But they don't develop the skills they need to get on well with others or to keep up in school.

With autism, your child usually has problems with speaking. And they may not like being touched in any way, such as cuddling. Also, they may behave in odd ways. For example, your child may do the same activity over and over. Or they may follow the same routine all the time.

Sometimes, children with autism are very good at a certain skill or subject, such as maths, technical drawing or music. That's because they can focus very hard on just one thing. This is linked to their autism. But it is rare.

Autism affects different children in different ways. Some children never learn to speak and need help all their lives. Other children can learn the skills they need to live on their own.

Autism belongs to a group of similar conditions. Doctors call this group autistic spectrum disorder. The group also includes a condition called Asperger syndrome. For more, see Autistic spectrum disorder.

On these pages, we are looking at autism itself.

Why my child?

If your child has autism, you may worry that something you did caused it. But nothing you have done as a parent could have caused your child's autism.

In fact, in most cases, doctors don't know the exact cause of autism.[6] All we know is that the brains of children with autism work in a different way.[1]

Researchers have looked at many factors to see if they are linked to autism. Some of them are listed below.

Genes and your family

Most researchers agree that a child's genes are the main reason for autism. You get half of your genes from your father and half from your mother.

Your genes control how your body develops. If you have a faulty gene, it can cause problems with growth and health. But this doesn't always happen.

A combination of certain faulty genes from both parents may increase a child's chances of getting autism. We're still not sure which genes are involved or how the faulty genes affect your child's brain.

Studies give us good evidence that autism is caused by genes, rather than by any things your baby or child experiences.

  • Some studies have looked at autism in families. When a family has one child with autism, the chances of having another child with autism are about 1 in 20.[7] This is much higher than we would expect.[6]
  • Other studies have looked at twins who match. Matching twins have the same genes. These studies have shown that if one twin has autism, the chance that the other twin has autism is from 6 in 10 to 9 in 10.[8] This is a much higher chance than for twins who don't match. Twins who don't match don't have the same genes.

If you already have a child with autism, or you or your partner has an autistic spectrum disorder, you may worry about the chances of your future children also having autism. You can get advice about this from a genetic counsellor. This is a person who will look closely at your family. Ask your GP or family doctor about this.

Things your child goes through

The genes your child has may not be the only reason for autism. Things your child goes through in the womb, at birth or afterwards might help bring on the condition. Autism probably happens because of a combination of genes and these other things. But researchers haven't found any good evidence for this. So we can't say for sure.[9]

Medical conditions

Sometimes autism is caused by a medical condition that your child gets. But this isn't common.[8] In about 1 in 10 children with autism, the autism is clearly caused by a medical condition.[9] For more, see Medical causes of autism.

MMR vaccine

In the past, some experts worried that vaccination with the MMR vaccine (a vaccine for measles, mumps and rubella) might be linked to autism. Because of the worry, many parents have decided not to give their children this vaccine. But several big studies have looked into this question. They have all said there isn't any evidence of a link between the MMR vaccine and autism.

Leading researchers and doctors who specialise in child health advise parents to give their children the MMR vaccine.[8] [10] [11] [12]

For more, see MMR vaccine and autism.

References

  1. Volkmar FR, Pauls D. Autism. Lancet. 2003; 362: 1133-1141. [Erratum in: Lancet. 2004 17; 363: 250.]
  2. Medline Plus. Developmental Milestones. Available at http://www.nlm.nih.gov/medlineplus/ency/article/002348.htm (accessed on 18 January 2006).
  3. Committee on Children with Disabilities. Technical report: the pediatrician's role in the diagnosis and management of autistic spectrum disorder in children. Pediatrics 2001; 107: 85. Available at http://pediatrics.aappublications.org/cgi/content/full/107/5/e85 (accessed on 23 November 2006).
  4. American Academy of Neurology and Child Neurology Society. Practice parameter: screening and diagnosis of autism. Available at http://www.guidelines.gov (accessed on 16 December 2005).
  5. Johnson CP. New tool helps primary care physicians diagnose autism early. AAP News. 2004; 24: 74. Available at http://aapnews.aappublications.org/cgi/content/full/24/2/74 (accessed on 15 December 2005).
  6. Folstein SE. Autism. International Review of Psychiatry. 1999; 11: 4.
  7. Bolton P, Macdonald H, Pickles A, et al. A case-control family history study of autism. Journal of Child Psychology and Psychiatry. 1994; 35: 877-900.
  8. Lamb JA, Parr JR, Bailey AJ, et al. Autism: in search of susceptibility genes. Neuromolecular Medicine. 2002; 2: 11-28.
  9. Medical Research Council. MRC review of autism research: epidemiology and causes. December 2001. Available at http://www.mrc.ac.uk/pdf-autism-report.pdf (accessed on 9 June 2005).
  10. Royal College of Paediatrics and Child Health, Faculty of Public Health Medicine, Public Health Medicine Environment Group and Community Practitioners and Health Visitors Association. Endorsing the continued use of the MMR triple vaccine. February 2002. Available at http://www.rcpch.ac.uk/publications (accessed on 15 December 2005).
  11. Wilson K, Mills E, Ross C, et al. Association of autistic spectrum disorder and the measles, mumps, and rubella vaccine: a systematic review of current epidemiological evidence. Archives of Pediatrics and Adolescent Medicine. 2003; 157: 628-634.
  12. Drug and Therapeutics Bulletin. MMR vaccine: how effective and how safe? Drug and Therapeutics Bulletin. 2003; 41: 25-29.

Glossary

genes
Your genes are the parts of your cells that contain instructions for how your body works. Genes are found on chromosomes, structures that sit in the nucleus at the middle of each of your cells. You have 23 pairs of chromosomes in your normal cells, each of which has thousands of genes. You get one set of chromosomes, and all of the genes that are on them, from each of your parents.

© BMJ Publishing Group Limited ("BMJ Group") 2007. All rights reserved

This information does not replace medical advice. If you are concerned you might have a medical problem please ask your Boots pharmacy team in your local Boots store, or see your doctor.

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